Organ support & nutrition

Major determinants of primary non function from kidney donation after Maastricht II circulatory death: A single center experience

J Crit CarePublished Retrospective cohort study

Authors' conclusion

Cannulation time and ANOR were the main factors that correlated with PNF.

Study context

Population
Kidney transplant recipients of Maastricht type 2 DCD grafts at an ECMO referral centrerenal grafts from 24 uDCD donors
Participants
47 recipients
Outcome
Early graft function and factors that impact on it
Methodological detailssingle-centre, October 2017 to December 2022
  • Single-centre
  • October 2017 to December 2022

Main finding

As reported in the abstract

Early graft function
Immediate graft function
25%
Delayed graft function
63.6%
Primary non-function (PNF)
11.4%
Correlation of cannulation time with PNF
p = 0.006
Correlation of ANOR duration with PNF
p = 0.016

Observational data: associations, not effects.

Further findings

Donor procedure times

min

Median warm ischemia time
106 (94-115)
Cannulation time
10 (8; 20)
Duration of extracorporeal reperfusion (ANOR)
180 (126-214)

Original publication

Major determinants of primary non function from kidney donation after Maastricht II circulatory death: A single center experience. J Crit Care. Published 10 April 2024. doi:10.1016/j.jcrc.2024.154811

Composed by AI from the published abstract and checked against it. How Briefs are made →

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