Mannitol clearance for assessment of glomerular filtration rate in critically ill patients
Performance · Agreement of mannitol multi-sample plasma clearance with iohexol clearance (reference)Result — go to the resultbias 2.9 ml/min/1.73 m²Authors' conclusion
In critically ill patients, plasma clearance of mannitol showed acceptable agreement with iohexol clearance, for both multi-and single-sample measurements.
Study context
- Population
- Intensive care unit (ICU) patients receiving simultaneous bolus injections of mannitol and iohexol
- Participants
- 20 patients
- Comparison
- Mannitol plasma clearance vs iohexol multi-sample plasma clearance
- Outcome
- Agreement (bias, error) and accuracy (P30, P10) of mannitol clearance vs iohexol clearance for measuring glomerular filtration rate (GFR)
Methodological detailsmulti-sample and one-sample plasma clearance, Bland-Altman agreement
- Multi-sample and one-sample plasma clearance
- Bland-Altman agreement
Performance
As reported in the abstract
Agreement of mannitol multi-sample plasma clearance with iohexol clearance (reference)
bias
2.9 ml/min/1.73 m²
- Accuracy of mannitol clearance vs reference, P30
- 85%
- Accuracy of mannitol clearance vs reference, P10
- 60%
Original publication
Mannitol clearance for assessment of glomerular filtration rate in critically ill patients. J Crit Care. Published 2 September 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →