Perioperative medicine & outcomes
Mapping Perioperative Care Randomized Controlled Trials in Sub-Saharan Africa: A Scoping Review
Authors' conclusion
This scoping review provides a comprehensive overview of perioperative care RCTs in SSA, highlighting limitations such as small sample sizes, under-representation of high surgical burden disciplines, and poor outcome reporting.
Study context
- Population
- Perioperative care randomized controlled trials (RCTs) conducted in sub-Saharan Africa, published 2000–2022
- Participants
- 45,376 participants · 169 RCTs
- Primary endpoint
- Geographical distribution, characteristics and reporting quality (CONSORT-2010) of included RCTs
Methodological detailsPRISMA-ScR, duplicate screening and extraction
- PRISMA-ScR
- Duplicate screening and extraction
Primary result
As reported in the abstract
Geographical distribution, characteristics and reporting quality of perioperative care RCTs in SSA, 2000–2022
- Eligible RCTs identified (of 3319 records)
- 169
- Participants randomised
- 45,376
- Mean sample size
- 98
- Countries in sub-Saharan Africa (SSA)
- 16
- Led by authors from Nigeria
- 63/169, 37.3 %
- Led by authors from South Africa
- 41/169, 24.3%
- Interventions conducted intraoperatively
- n = 125/169, 74%
- Pharmacotherapy interventions
- n = 64/169, 37.9%
- Analgesic interventions
- n = 42/169, 24.9%
- Obstetrics, most investigated surgical discipline
- n = 51/169, 30.2%
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Mapping Perioperative Care Randomized Controlled Trials in Sub-Saharan Africa: A Scoping Review. Anesth Analg. Published 13 March 2025. doi:10.
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