Respiratory failure & ventilation
Mechanically Ventilated Patients With Coronavirus Disease 2019 Had a Higher Chance of In-Hospital Death If Treated With High-Flow Nasal Cannula Oxygen Before Intubation
Main finding · In-hospital deathResult — go to the resultHazard ratio 2.08 95% CI 1.06–4.05Authors' conclusion
Among patients with respiratory failure from COVID-19 requiring mechanical ventilation, patients receiving HFNC before intubation had a higher chance of in-hospital death.
Study context
- Population
- Patients with COVID-19-related respiratory failure requiring high-flow nasal cannula (HFNC), intubation or both, March 2020 to March 2021
- Participants
- 440 patients
- Exposure
- HFNC before intubation vs intubation without prior HFNC
- HFNCn = 311
- Intubation onlyn = 129reference
- Outcome
- Successful extubation and in-hospital mortality
Methodological detailssingle-centre
- Single-centre
Main finding
In-hospital death
Hazard ratio
2.08
95% CI 1.06–4.05
HFNC vs Intubation only
HR 2.08 (95% CI 1.06–4.05)
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | Estimate |
|---|---|
| Successful extubationNo difference | 0.70 (CI 0.41–1.20) |
Original publication
Mechanically Ventilated Patients With Coronavirus Disease 2019 Had a Higher Chance of In-Hospital Death If Treated With High-Flow Nasal Cannula Oxygen Before Intubation. Anesth Analg. Published 4 November 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →