Respiratory failure & ventilation
Methods to monitor and evaluate neuromuscular blockade use in intensive care unit patients with hypoxemic respiratory failure and acute respiratory distress syndrome: a scoping review
Authors' conclusion
Current evidence suggests the use of a protocol to guide NMBA monitoring and dosing in the ICU may be associated with benefits.
Study context
- Population
- Adults on invasive mechanical ventilation for hypoxemic respiratory failure (HRF) and acute respiratory distress syndrome (ARDS) in the intensive care unit (ICU)
- Participants
- 994 adults · 12 studies
- Comparison
- NMBA monitoring strategies: peripheral nerve stimulation with TOF monitoring and clinical assessment
- Outcome
- NMBA monitoring strategies and associated outcomes
Methodological details2,274 records identified, 402 full-text reviewed
- 2,274 records identified, 402 full-text reviewed
Main finding
As reported in the abstract
- Protocol-guided NMBA monitoring and administration (studies)
- 9
Original publication
Methods to monitor and evaluate neuromuscular blockade use in intensive care unit patients with hypoxemic respiratory failure and acute respiratory distress syndrome: a scoping review. Can J Anaesth. Published 22 May 2026. doi:10.
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