Respiratory failure & ventilation
Effect of therapeutic interventions combined with lung-protective ventilation on long-term mortality of patients with acute respiratory distress syndrome: a network meta-analysis
Authors' conclusion
Prone positioning may improve long-term mortality in patients with ARDS.
Study context
- Population
- Adults with acute respiratory distress syndrome (ARDS)
- Participants
- 8,653 adults · 22 trials
- Comparison
- Interventions added to lung-protective ventilation (LPV) vs LPV alone
- Outcome
- 180-day mortality
- Follow-up
- 180 days
Methodological detailsBayesian random effects fractional polynomial models, network meta-analysis (NMA) of survival curves
- Bayesian random effects fractional polynomial models
- NMA of survival curves
Pooled result
As reported in the abstract
LPV alone
0.52
survival probability · 95% CrI 0.49–0.55
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Effect of therapeutic interventions combined with lung-protective ventilation on long-term mortality of patients with acute respiratory distress syndrome: a network meta-analysis. Can J Anaesth. Published 4 March 2026. doi:10.
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