Cardiothoracic & vascular anesthesia

Mitral Valve Coaptation Reserve Index: A Model to Localize Individual Resistance to Mitral Regurgitation Caused by Annular Dilation

J Cardiothorac Vasc AnesthPublished Retrospective mechanistic study

Authors' conclusion

Quantification and indexing of mitral coaptation reserve along the closure line are feasible. Indexing and mathematical simulation of progressive annular dilatation consistently showed that indexed coaptation reserve was lowest in the A2-to-P2 region.

Study context

Population
Patients with normally functioning mitral valves undergoing cardiac surgery
Participants
25 patients
Outcome
Leaflet coaptation (reserve) along the closure line per segment (A1-P1, A2-P2, A3-P3), and the indexed CRI after simulated progressive annular dilation
Methodological detailssingle-centre, mathematical modelling, intraoperative 3D TEE datasets
  • Single-centre
  • Mathematical modelling
  • Intraoperative 3D TEE datasets

Main finding

As reported in the abstract

Coaptation reserve along the closure line (direct measurement)

Observational data: associations, not effects.

Original publication

Mitral Valve Coaptation Reserve Index: A Model to Localize Individual Resistance to Mitral Regurgitation Caused by Annular Dilation. J Cardiothorac Vasc Anesth. Published 13 November 2022. doi:10.1053/j.jvca.2022.11.009

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