Pediatric anesthesia & critical care
Modeling iatrogenic intraoperative hyperthermia from external warming in children: A pooled analysis from two prospective observational studies
Authors' conclusion
In children, external warming by forced-air needs to be closely monitored and adjusted in a timely manner to avoid iatrogenic hyperthermia especially during long procedures, in young age, higher surface-area-to-weight ratio, and higher baseline temperature.
Study context
- Population
- Anesthetized children aged 6 years or younger receiving forced-air warming55 female
- Participants
- 200 children
- Outcome
- Course of core temperature over time (quadratic regression model)
Methodological detailspooled data
- Pooled data
Pooled result
As reported in the abstract
Core temperature increase over time
Mean temperature increase after 1 h
0.43°C
Mean temperature increase after 2 h
0.64°C
Peak mean temperature increase
0.66°C
Time of peak
147 min
Further pooled results
| Outcome | Estimate | |
|---|---|---|
| Hyperthermia per 10 min of warming (model with age)Ceteris paribus | OR 1.14 (95% CI 1.07–1.22) | |
| Hyperthermia per 10 min of warming (model with surface-area-to-weight ratio)Ceteris paribus | OR 1.13 (95% CI 1.06–1.21) | |
| Hyperthermia per 1-year decrease in ageCeteris paribus | OR 1.33 (95% CI 1.07–1.71) | |
| Hyperthermia per 0.01 increase in surface-to-weight-area ratioCeteris paribus | OR 1.63 (95% CI 0.93–2.83) | |
| Hazard of hyperthermia per 0.1°C increase in baseline temperatureCox proportional hazards model | HR 1.33 (95% CI 1.23–1.43) | |
| 0.20.5125Ratio (log scale) |
Incidence of hyperthermia (core temperature >38°C) at ≥1 measurement point
- Children hyperthermic at at least one measurement point
- 33
Original publication
Modeling iatrogenic intraoperative hyperthermia from external warming in children: A pooled analysis from two prospective observational studies. Paediatr Anaesth. Published 30 October 2022. doi:10.
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