Pediatric anesthesia & critical care
Monitoring anesthesia depth with patient state index during pediatric surgery
Authors' conclusion
NonpEEG-guided anesthesia in children led to median patient state index levels at the low range of recommended unconsciousness values with frequent episodes of burst suppression. Patient state index levels were generally higher in children below 2 years.
Study context
- Population
- Children aged 1–18 years undergoing surgery longer than 60 min under GA conducted according to indirect evaluation of depthenrolled
- Participants
- 111 children
- Outcome
- Median patient state index (PSI) and spectral edge frequency 95% (SEF95) values
Methodological detailsSedLine monitor with pediatric sensors; PSI recorded at predefined time points until discharge to ward
- SedLine monitor with pediatric sensors; PSI recorded at predefined time points until discharge to ward
Main finding
As reported in the abstract
Patient state index
- PSI at end of induction, median (IQR)
- 25 (22-32)
- PSI in maintenance phase, median range
- 26 (23-34) to 28 (25-36)
- PSI at extubation
- 48 (35-60)
- PSI at discharge from operating room
- 69 (62-75)
- Right/left SEF95 at end of induction (Hz)
- 10 (6-14)/9 (5-14)
- SEF95 in maintenance phase, both hemispheres (Hz)
- 10 (6-14) to 12 (11-15)
- Right/left SEF95 at extubation (Hz)
- 18 (15-21)/17 (15-21)
Observational data: associations, not effects.
Further findings
Burst suppression and postoperative delirium (PAED)
| OR (95% CI) | P value | ||
|---|---|---|---|
| Burst suppressionNot associated | 1.58 (0.14–16.74) | p` = .18 | |
| 0.050.21520Odds ratio (log scale) |
Burst suppression
- Episodes of burst suppression
- 39
- Patients with burst suppression
- 20 (19%)
PSI by type of anesthesia
- Median PSI not different between inhalational and IV anesthesia, nor between GA and GA plus locoregional anesthesia
PSI by age (subgroup)
- Significantly higher PSI in children <2 years than older patients
- P = 0.0004
Original publication
Monitoring anesthesia depth with patient state index during pediatric surgery. Paediatr Anaesth. Published 19 June 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →