Hemodynamics, fluids & transfusion

Mottling as a prognosis marker in cardiogenic shock

Ann Intensive CarePublished Prospective observational registry study

Authors' conclusion

Skin mottling at admission in patients with cardiogenic shock was statistically associated with prolonged length of stay and poor outcomes.

Study context

Population
Patients admitted for cardiogenic shock of all etiologies, French critical care units, April–October 2016 (FRENSHOCK)660 assessed for mottling
Participants
772 patients
Exposure
Skin mottling vs no mottling at admission
Outcome
Mortality
Follow-up
30 days and 1 year
Methodological detailsmulticentre
  • Multicentre

Main finding

As reported in the abstract

30-day mortality, mottling vs no mottling

31% vs. 23.3%

p = 0.031

1-year mortality, mottling vs no mottling

54% vs. 42%

p = 0.003

Observational data: associations, not effects.

Further findings

Need for invasive respiratory support

P < 0.001

Need for RRT

P = 0.09

LOS

P = 0.033

Need for mechanical circulatory support

Similar in both groups

30-day prognosis, mottling appearing within first 24 h (subgroup)

Worst prognosis at 30 days

Original publication

Mottling as a prognosis marker in cardiogenic shock. Ann Intensive Care. Published 6 September 2023. doi:10.1186/s13613-023-01175-0

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