Pediatric anesthesia & critical care
Multicenter Assessment of Cryoanalgesia Use in Minimally Invasive Repair of Pectus Excavatum: A 20-center Retrospective Cohort Study
Authors' conclusion
Use of cryoanalgesia during MIRPE appears to be effective in lowering postoperative opioid requirements and LOS without increasing complication rates.
Study context
- Population
- Children (age <18 years) undergoing minimally invasive repair of pectus excavatum (MIRPE), 20 US children's hospitals, January 1, 2014 to August 1, 2019
- Participants
- 898 children · 20 hospitals
- Exposure
- Cryoanalgesia vs no cryoanalgesia during MIRPE
- Outcome
- Total postoperative inpatient oral morphine equivalents per kilogram and 30-day length of stay (LOS)
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
Cryoanalgesia vs No cryoanalgesiaRelative risk (95% CI)
Oral morphine equivalents per kg
0.43(0.33–0.57)
LOS
0.66(0.50–0.87)
Observational data: associations, not effects.
Safety
| Outcome | P value |
|---|---|
| ComplicationsCryoanalgesia vs No cryoanalgesia · 29.8% vs 22.1 | P = 0.07 |
Complications
- Similar rate of ED visit, readmission and/or reoperation
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Multicenter Assessment of Cryoanalgesia Use in Minimally Invasive Repair of Pectus Excavatum: A 20-center Retrospective Cohort Study. Ann Surg. Published 6 July 2022. doi:10.
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