Perioperative medicine & outcomes

Multicentre prospective study on the diagnostic and prognostic validity of malnutrition assessment tools in surgery

Br J SurgPublished Diagnostic accuracy study

Authors' conclusion

This study supports the use of the MUST as it is the most valid nutritional screening tool in patients after major abdominal surgery.

Study context

Population
Consecutive patients undergoing elective or emergency major abdominal surgery for benign or malignant disease, 12 Greek hospitals, January 2022–December 2023
Participants
1,649 patients · 12 Greek hospitals
Comparison
Malnutrition assessment tools vs subjective global assessment (SGA) as reference standard
Outcome
Diagnostic accuracy vs SGA
Methodological detailsprospective, multicentre
  • Prospective
  • Multicentre

Performance

As reported in the abstract

Test or modelAUCDiagnostic OR
MNA-SF0.83 (95% c.i. 0.81 to 0.85)30.2 (95% c.i. 20.2 to 45.1)
MUST0.79 (95% c.i. 0.77 to 0.82)16.1 (95% c.i. 12.4 to 21.1)

AUC

MNA-SF0.83 (95% c.i. 0.81 to 0.85)
MUST0.79 (95% c.i. 0.77 to 0.82)

Diagnostic OR

MNA-SF30.2 (95% c.i. 20.2 to 45.1)
MUST16.1 (95% c.i. 12.4 to 21.1)

Further findings

OutcomeValues
Malnutrition by SGASGA 34.1%
Malnutrition risk by screening toolsNRS-2002 24.0% · MNA-SF 58.6%

Malnutrition by SGA

SGA had excellent construct and prognostic validity

Malnutrition risk by screening tools

Range across tools from 24.0% (NRS-2002) to 58.6% (MNA-SF)

Construct and prognostic validity of MUST

MUST performed well in construct and prognostic validity appraisals

Original publication

Multicentre prospective study on the diagnostic and prognostic validity of malnutrition assessment tools in surgery. Br J Surg. Published 3 March 2025. doi:10.1093/bjs/znaf013

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