Perioperative medicine & outcomes
Multidisciplinary prehabilitation to improve frailty and functional capacity in high-risk elective surgical patients: a retrospective pilot study
Authors' conclusion
This outpatient-based, one-stop multidisciplinary prehabilitation programme was feasible, safe, and improved several measures of patient's physiological reserve and functional capacity.
Study context
- Population
- High-risk frail patients undergoing major elective surgery (high risk of frailty or malnutrition, or major hepatectomy, esophagectomy, pancreaticoduodenectomy or radical cystectomy)72 of 111 eligible
- Participants
- 54 patients
- Outcome
- Feasibility and safety of prehabilitation
Methodological detailssingle-centre, Dec 2020-Nov 2021
- Single-centre
- Dec 2020-Nov 2021
Main finding
As reported in the abstract
Feasibility (adherence to 3 weeks of prehabilitation) and safety
Prehabilitation
96.3%
52 of 54
- Eligible for prehabilitation
- 72 out of 111 patients (64.9%)
- Recruited of eligible
- 54 (75%)
Observational data: associations, not effects.
Secondary outcomes
Exercise capacity
- Improved with prehabilitation
- P = 0.08
Functional mobility measures
- Some measures enhanced with prehabilitation
- P = 0.02
Nutritional energy intake
- Increased with prehabilitation
- P = 0.04
Protein intake
- Increased with prehabilitation
- P < 0.01
Muscle strength, cognitive function, emotional resilience
- Prehabilitation-related changes minimal
DAH30 · 30 days after surgery
- Median (IQR) DAH30, days
- 19 (14-23)
Safety
- No adverse events reported
Original publication
Multidisciplinary prehabilitation to improve frailty and functional capacity in high-risk elective surgical patients: a retrospective pilot study. Perioper Med (Lond). Published 23 January 2024. doi:10.
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