Multimodal pain management and postoperative outcomes in inpatient and outpatient shoulder arthroplasties: a population-based study
Main finding · Opioid charges (OME), inpatients, >2 modes without nerve block vs opioid-onlyResult — go to the resultAdjusted % change −19.4% 95% CI −21.2% to −17.6%Authors' conclusion
Multimodal analgesia is associated with reductions in opioid charges-specifically inpatient setting-but not various other outcomes.
Study context
- Population
- Patients undergoing inpatient or outpatient (reverse, total, partial) shoulder arthroplasty, 2010 to 2019
- Participants
- 176,225 procedures
- Exposure
- Multimodal analgesia vs opioid-only analgesia
- Outcome
- Opioid charges (oral morphine equivalents, oral morphine equivalents (OME))
Methodological detailspopulation-based, Premier Healthcare Database, multivariable regression
- Population-based
- Premier Healthcare Database
- Multivariable regression
Main finding
As reported in the abstract
Opioid charges (OME), inpatients, >2 modes without nerve block vs opioid-only · POD 1
Adjusted % change
−19.4%
95% CI −21.2% to −17.6%
By group
Multimodal analgesia vs Opioid-only analgesia
adjusted % change −19.4% (95% CI −21.2% to −17.6%)
Observational data: associations, not effects.
Further findings
| Outcome | Adjusted % change (%) (95% CI) | |
|---|---|---|
| Opioid charges (OME), total hospitalization, inpatients, >2 modes without nerve blockUnadjusted median OME reductions from 173 to 135 mg | −6.0 (−7.2% to −4.9%) | |
| −10−505Difference, % (linear scale) |
Opioid charges with nerve block added to multimodal analgesia (inpatient and outpatient)
- Addition of a nerve block to multimodal analgesia attenuated effects on opioid charges in both settings
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Multimodal pain management and postoperative outcomes in inpatient and outpatient shoulder arthroplasties: a population-based study. Reg Anesth Pain Med. Published 18 March 2024. doi:10.
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