Hemodynamics, fluids & transfusion
Multimodal Perfusion Assessment in Hemodynamically Unstable Patients: A Concise Definitive Review
Authors' conclusion
Multimodal perfusion assessment should be interpreted as an integrated physiologic process rather than a search for a single superior marker.
Study context
- Population
- Hemodynamically unstable (critically ill) patients
- Outcome
- Perfusion monitoring modalities
Methodological detailsconcise definitive review, Tools reviewed: capillary refill time, peripheral perfusion indices, serum lactate, venous oxygenation variables, tissue oxygenation, spectral imaging, advanced hemodynamic assessments, RCTs, observational studies, physiologic investigations, narrative and systematic reviews considered
- Concise definitive review
- Tools reviewed: capillary refill time, peripheral perfusion indices, serum lactate, venous oxygenation variables, tissue oxygenation, spectral imaging, advanced hemodynamic assessments
- RCTs, observational studies, physiologic investigations, narrative and systematic reviews considered
Main finding
As reported in the abstract
- Multimodal perfusion assessment should be interpreted as an integrated physiologic process rather than a search for a single superior marker
- Capillary refill time provides a pragmatic clinical anchor; complementary tools may refine interpretation when physiologic coherence is uncertain
- Escalation of monitoring should be guided by patient risk and unresolved uncertainty
Original publication
Multimodal Perfusion Assessment in Hemodynamically Unstable Patients: A Concise Definitive Review. Crit Care Med. Published 4 June 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →