National incidence and mortality of hospitalized sepsis in China
Authors' conclusion
Our study showed a greater burden of sepsis hospitalizations than previous estimated.
Study context
- Population
- Hospitalized sepsis in China, 2017–2019 (National Data Center for Medical Service (NDCMS) and National Mortality Surveillance System (NMSS))
- Participants
- 9,455,279 participants · 10,682,625 sepsis admissions
- Outcome
- Population-based incidence and geographic variation of hospitalized sepsis
Methodological detailsnationwide, ICD-10 code identification
- Nationwide
- ICD-10 code identification
Main finding
As reported in the abstract
Annual standardized incidence of hospitalized sepsis (cases per 100,000)
2017
328.25
95% CI 315.41–341.09
2018
359.26
95% CI 345.4–373.12
2019
421.85
95% CI 406.65–437.05
Observational data: associations, not effects.
Further findings
Share of incidence by age
- Neonates <1 year
- 8.7%
- Children 1-9 years
- 11.7%
- Elderly >65 years
- 57.5%
Spatial autocorrelation of incidence (Moran's Index)
- 2017
- 0.42, p = 0.001
- 2018
- 0.45, p = 0.001
- 2019
- 0.26, p = 0.011
Sepsis-related deaths in NMSS
- Sepsis-related deaths
- 806,728
Associations with incidence
- Higher hospital bed supply and higher disposable income per capita significantly associated with higher incidence
Original publication
National incidence and mortality of hospitalized sepsis in China. Crit Care. Published 4 March 2023. doi:10.
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