Temporal trends of sepsis-related mortality in China, 2006–2020: a population-based study
Authors' conclusion
Despite declining trends of age-standardized mortality and YLLs of sepsis in China, significant disparities between population groups and regions
Study context
- Population
- Sepsis-related deaths in China's National Mortality Surveillance System, 2006–2020
- Outcome
- Temporal trends of sepsis-related mortality and years of life lost (YLLs)
Methodological detailsnational mortality surveillance data, Joinpoint regression analysis
- National mortality surveillance data
- Joinpoint regression analysis
Main finding
As reported in the abstract
Sepsis-related mortality and YLLs · 2006 to 2020
- Sepsis-related deaths in 2020
- 986,929
- Sepsis years of life lost (YLLs) in 2020
- 17.1 million
- Age-standardized sepsis-related mortality per 100,000 population, 2006
- 130.2 (95% CI 129.4-131)
- Age-standardized sepsis-related mortality per 100,000 population, 2020
- 76.6 (95% CI 76.3-76.9)
- Age-standardized YLLs per 100,000 population, 2006
- 2172.7 (95% CI 2169.4-2176)
- Age-standardized YLLs per 100,000 population, 2020
- 1271 (95% CI 1269.8-1272.2)
Observational data: associations, not effects.
Further findings
Variation by population group and region
- Higher burden in males, the elderly, and western China
Association of sociodemographic index (SDI) with sepsis-related mortality or YLLs
- Inverse relation between SDI and sepsis-related mortality or YLLs
Original publication
Temporal trends of sepsis-related mortality in China, 2006–2020: a population-based study. Ann Intensive Care. Published 14 August 2023. doi:10.
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