Regional anesthesia

Neurological injury following peripheral nerve blocks: a narrative review of estimates of risks and the influence of ultrasound guidance

Reg Anesth Pain MedPublished Narrative review with pooled estimates

Authors' conclusion

Our review adds information to existing literature that the neurological complications are rarer but seem to display a higher incidence for some blocks more than others.

Study context

Population
Patients receiving peripheral nerve blocks (PNB)
Exposure
With vs without US guidance; individual PNBs
Outcome
Incidence of post-block neurological dysfunction (PBND): new-onset sensorimotor disturbances in the distribution of the performed PNB
Follow-up
>48 hours to <2 weeks; >2 weeks to 6 weeks, 7 weeks to 5 months, 6 months to 1 year and >1 year
Methodological detailsprospective and retrospective studies, six databases
  • Prospective and retrospective studies
  • Six databases

Main finding

As reported in the abstract

Overall incidence of PBND

Incidence per thousand at <2 weeks (95% CI 8; to 11), ≈1%

9

Incidence per thousand at 1 year (95% CI 0.1; to 0.5), ≈3/10 000

0. 3

Observational data: associations, not effects.

Further findings

Post-block neurological dysfunction (PBND) by individual PNB

Incidence differed for individual PNB, highest for interscalene block

Original publication

Neurological injury following peripheral nerve blocks: a narrative review of estimates of risks and the influence of ultrasound guidance. Reg Anesth Pain Med. Published 8 November 2023. doi:10.1136/rapm-2023-104855

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