ICU sedation, delirium & recovery
New prognostic score for mortality in critically ill patients. Development and validation
Authors' conclusion
A validated NMP model was developed using nine additional risk factors alongside APACHE II.
Study context
- Population
- Adults (>18 years) admitted to the ICU, 167 Spanish hospitals (193 ICUs), over 7 years91,777 estimation
- Participants
- 137,666 adults
- Comparison
- New prognostic model vs APACHE II alone
- Outcome
- ICU mortality
Methodological detailspost-hoc analysis, multicentre, prospective data, multivariable logistic regression, separate validation cohort
- Post-hoc analysis
- Multicentre
- Prospective data
- Multivariable logistic regression
- Separate validation cohort
Performance
As reported in the abstract
Discrimination for ICU mortality
| Test or model | AUROC |
|---|---|
| New model | 0.872 |
| APACHE II | 0.826 |
AUROC
New model0.872
APACHE II0.826
%
- ICU mortality (overall)
- 10.8
- Reclassification improvement over APACHE II
- 52
- Survivors reclassified
- 19.4
- Non-survivors reclassified
- 32.75
Original publication
New prognostic score for mortality in critically ill patients. Development and validation. J Crit Care. Published 1 August 2025. doi:10.
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