ICU sedation, delirium & recovery
Urea to creatinine ratio as a predictor of persistent critical illness
Authors' conclusion
In this single center retrospective cohort study, UCr was not found to be associated with PCI development.
Study context
- Population
- Patients admitted to a general mixed medical-surgical ICU, Jan 1st 2018 till Dec 31st 2022included in the analysis
- Participants
- 2,098 patients
- Exposure
- Persistent critical illness (PCI) vs non-PCI patients; association of Urea to Creatinine ratio (UCr) with PCI development
- Outcome
- Association between UCr and PCI development
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
UCr and PCI development
- Significant difference in UCr only on the first admission day among all patients; not found separately in surgical, trauma, or transplantation patients
- No difference in UCr in different KDIGO stages
Observational data: associations, not effects.
Further findings
90-day mortality
P < 0.0001
1 year mortality (multivariate Cox regression)
- Elevated UCr and PCI significantly associated with 1 year mortality
Baseline characteristics
- PCI patients older, with higher admission prognostic scores
Original publication
Urea to creatinine ratio as a predictor of persistent critical illness. J Crit Care. Published 22 May 2024. doi:10.
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