Pediatric anesthesia & critical care

Nomograms Based on Myocardial Strain and Myocardial Work to Predict Low Cardiac Output Syndrome in Children Undergoing Surgery for Congenital Heart Disease

J Cardiothorac Vasc AnesthPublished Retrospective observational study

Authors' conclusion

We developed a nomogram model incorporating GLS, GWI, and GWE to predict postoperative LCOS in children undergoing CHD surgery. The model demonstrated favorable discrimination, calibration, and clinical applicability

Study context

Population
Children undergoing elective congenital heart disease (CHD) surgery under cardiopulmonary bypass (CPB), January 2023–December 2024
Participants
155 children
Outcome
LCOS
Follow-up
Within 24 hours postoperatively
Methodological detailsprediction model development, single-centre, tertiary care center, nomogram
  • Prediction model development
  • Single-centre
  • Tertiary care center
  • Nomogram

Main finding

As reported in the abstract

Nomogram performance for predicting postoperative LCOS
Low cardiac output syndrome (LCOS) incidence within 24 h postoperatively
31 (20.0%)
AUC
0.872 (95% CI 0.793-0.951, p < 0.001)
Sensitivity
74.2%
Specificity
88.7%
Calibration mean absolute error
0.021

Observational data: associations, not effects.

Original publication

Nomograms Based on Myocardial Strain and Myocardial Work to Predict Low Cardiac Output Syndrome in Children Undergoing Surgery for Congenital Heart Disease. J Cardiothorac Vasc Anesth. Published 27 September 2025. doi:10.1053/j.jvca.2025.09.228

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