Respiratory failure & ventilation

Non-invasive over-distension measurements: data driven vs model-based

J Clin Monit ComputPublished Method comparison study

Authors' conclusion

The proposed OD offers an efficient, general, real-time measurement of patient-specific lung mechanics, which is more intuitive and robust than SI.

Study context

Population
Acute respiratory distress syndrome (ARDS) patients on mechanical ventilation (MV)196 cases
Participants
19 patients
Comparison
Non-invasive over-distension measurement vs stress index
Outcome
Correlation between OD and SI (R2 and Spearman rs)

Main finding

As reported in the abstract

Overall correlation between OD and SI

R2

0.76

Spearman rs

0.89

Further findings

Correlation by ARDS severity (subgroup)

Correlation higher considering only moderate and severe ARDS patients

OD safe range calibrated to stress index (SI) safe range (0.95-1.05)

OD safe range
0 ≤ OD ≤ 0.8 cmH2O
  • Calibrated by sensitivity and specificity test

Original publication

Non-invasive over-distension measurements: data driven vs model-based. J Clin Monit Comput. Published 3 August 2022. doi:10.1007/s10877-022-00900-7

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