Cardiac arrest & resuscitation

Non-prescription drug-associated out-of-hospital cardiac arrest: Changes in incidence over time and the odds of receiving resuscitation

ResuscitationPublished Retrospective cohort study

Main finding · Incidence trends and odds of EMS treatmentResult — go to the resultAdjusted odds ratio 1.34 95% CI 1.13–1.58

Authors' conclusion

Although EMS-treated DA-OHCA incidence increased by nearly three-fold, it comprised a minority of the overall OHCA increase during the study period. DA-OHCA was associated with an increased likelihood of EMS treatment.

Study context

Population
Consecutive non-traumatic adult out-of-hospital cardiac arrest (OHCA), provincial registry, 2016–2022
Participants
33,365 emergency medical services (EMS)-assessed cases
Exposure
Drug-associated OHCA vs non-drug-associated OHCA
Outcome
Incidence trends and odds of EMS treatment
Follow-up
2016 to 2022
Methodological detailsprovincial cardiac arrest registry
  • Provincial cardiac arrest registry

Main finding

As reported in the abstract

Adjusted odds ratio

1.34

95% CI 1.13–1.58

DA-OHCA vs Non-DA-OHCA
AOR 1.34 (95% CI 1.13–1.58)
EMS-treated OHCA incidence, 2016 to 2022 (per 100,000 person-years)
60 to 79
EMS-treated drug-associated OHCA (DA-OHCA) incidence, 2016 to 2022 (per 100,000 person-years)
3.7 to 9.1
Proportion of overall OHCA classified as DA-OHCA, 2016 to 2022
6.1% to 11.5%
DA-OHCA among EMS-treated OHCA
1,985/18,591 (11%)
DA-OHCA among EMS-untreated OHCA
887/9,200 (9.6%)

Observational data: associations, not effects.

Further findings

Characteristics of EMS-treated DA-OHCA
40 · median · IQR 31–51 · years

Original publication

Non-prescription drug-associated out-of-hospital cardiac arrest: Changes in incidence over time and the odds of receiving resuscitation. Resuscitation. Published 30 December 2023. doi:10.1016/j.resuscitation.2023.110107

Composed by AI from the published abstract and checked against it. How Briefs are made →

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