Pediatric anesthesia & critical care
Noninvasive respiratory support preventing reintubation after pediatric cardiac surgery—A systematic review
Authors' conclusion
We did not find clear evidence of a difference in reintubation rates and other clinical outcomes between different noninvasive ventilation strategies.
Study context
- Population
- Children (<16 years) after cardiac surgery and postoperative invasive ventilation, PICU or neonatal ICU6 studies included
- Comparison
- Noninvasive respiratory support strategies after extubation
- Outcome
- Extubation failure (defined as reintubation)
Methodological detailsno pooled synthesis, Evidence certainty very low, 167 studies screened; risk of bias low in 1, high in 1, some concerns in 4
- No pooled synthesis
- Evidence certainty very low
- 167 studies screened; risk of bias low in 1, high in 1, some concerns in 4
Pooled result
As reported in the abstract
Reintubation
Relative risk (95% CI)
HFNC vs COTindividual study
0.10(0.02–0.40)
HFNC vs COTindividual study
1.07(0.16–7.26)
HFNC vs NIPPV
0.49(0.05–5.28)
NHFOV vs CPAPprinted as HFNOV
0.40(0.08–1.94)
NHFOV vs NIPPVprinted as HFNOV
0.75(0.26–2.18)
CPAP vs NIPPV
1.37(0.33–5.73)
Further pooled results
Treatment duration
- Did not differ between the groups
Original publication
Noninvasive respiratory support preventing reintubation after pediatric cardiac surgery—A systematic review. Paediatr Anaesth. Published 1 December 2023. doi:10. 1111/ pan. 14808
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