Pediatric anesthesia & critical care

Noninvasive respiratory support preventing reintubation after pediatric cardiac surgery—A systematic review

Paediatr AnaesthPublished Systematic review of randomised controlled trials

Authors' conclusion

We did not find clear evidence of a difference in reintubation rates and other clinical outcomes between different noninvasive ventilation strategies.

Study context

Population
Children (<16 years) after cardiac surgery and postoperative invasive ventilation, PICU or neonatal ICU6 studies included
Comparison
Noninvasive respiratory support strategies after extubation
Outcome
Extubation failure (defined as reintubation)
Methodological detailsno pooled synthesis, Evidence certainty very low, 167 studies screened; risk of bias low in 1, high in 1, some concerns in 4
  • No pooled synthesis
  • Evidence certainty very low
  • 167 studies screened; risk of bias low in 1, high in 1, some concerns in 4

Pooled result

As reported in the abstract

Reintubation
Relative risk (95% CI)
HFNC vs COTindividual study
0.10(0.02–0.40)
HFNC vs COTindividual study
1.07(0.16–7.26)
HFNC vs NIPPV
0.49(0.05–5.28)
NHFOV vs CPAPprinted as HFNOV
0.40(0.08–1.94)
NHFOV vs NIPPVprinted as HFNOV
0.75(0.26–2.18)
CPAP vs NIPPV
1.37(0.33–5.73)

Further pooled results

Treatment duration

Did not differ between the groups

Original publication

Noninvasive respiratory support preventing reintubation after pediatric cardiac surgery—A systematic review. Paediatr Anaesth. Published 1 December 2023. doi:10.1111/pan.14808

Composed by AI from the published abstract and checked against it. How Briefs are made →

Get them every week

New studies on this topic in My Week and in your Monday e-mail.

We e-mail you a sign-in link and a code. No password, no spam.