Respiratory failure & ventilation

Noninvasive ventilation failure in thoracic trauma: A retrospective study on predictive scores, ventilatory strategies and pain management’

J Crit CarePublished Retrospective cohort study

Authors' conclusion

Higher HACOR and lower ROX scores at ICU admission were associated with NIV failure in blunt thoracic trauma patients.

Study context

Population
ICU patients with blunt thoracic trauma, S. Chiara Hospital (Trento, Italy)
Participants
93 patients
Exposure
NIV failure vs NIV success
  • NIV failuren = 20
  • NIV successn = 73reference
Outcome
NIV failure (need for invasive mechanical ventilation)
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

NIV succeeded (patients)

73

78.5 %

Required intubation (NIV failure) (patients)

20

21.5 %

Observational data: associations, not effects.

Further findings

OutcomeNIV successNIV failureP value
HACOR score at ICU admission25P = 0.002
ROX index at ICU admission14.48.5P = 0.006
NIV failure rate by NIV strategyAlternating helmet CPAP and HFNC vs Helmet CPAP aloneP = 0.05
Epidural analgesia use46.6 %— not stated in the abstractP = 0.004
Opioid use— not stated in the abstract90 %P = 0.016

— not stated in the abstract

  • NIV failure rate by NIV strategy: Alternating helmet CPAP and HFNC 13 %
  • NIV failure rate by NIV strategy: Helmet CPAP alone 31 %

Original publication

Noninvasive ventilation failure in thoracic trauma: A retrospective study on predictive scores, ventilatory strategies and pain management’. J Crit Care. Published 11 June 2025. doi:10.1016/j.jcrc.2025.155137

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