Respiratory failure & ventilation
A novel positive end-expiratory pressure titration using electrical impedance tomography in spontaneously breathing acute respiratory distress syndrome patients on mechanical ventilation: an observational study from the MaastrICCht cohort
Authors' conclusion
EIT-guided PEEP titration by the RPF approach is feasible and is linked to improved overall lung mechanics) during SMV using a threshold of approximately 5% CL.
Study context
- Population
- COVID-19 ARDS patients on spontaneous mechanical ventilation
- Participants
- 25 patients
- Exposure
- Electrical impedance tomography (EIT)-guided positive end expiratory pressure (PEEP) at pre-defined thresholds vs baseline PEEP
- Outcome
- Feasibility of regional peak flow (RPF) by EIT for PEEP titration during spontaneous mechanical ventilation (SMV); clinical and mechanical outcomes at thresholds vs baseline PEEP
Methodological detailssingle EIT measurements, MaastrICCht cohort
- Single EIT measurements
- MaastrICCht cohort
Main finding
As reported in the abstract
- Cyclic alveolar recruitment change across thresholds
- −3.9% to −37.9%
- Recruitment change across thresholds
- - 49.4% to + 79.2%
- Cumulative overdistension (OD) change across thresholds
- - 75.9% to + 373.4%
- Cumulative collapse (CL) change across thresholds
- 0% to −94.3%
- PEEP across thresholds (cmH2O) vs baseline 10 cmH2O
- 10 up to 14
Observational data: associations, not effects.
Original publication
A novel positive end-expiratory pressure titration using electrical impedance tomography in spontaneously breathing acute respiratory distress syndrome patients on mechanical ventilation: an observational study from the MaastrICCht cohort. J Clin Monit Comput. Published 28 August 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →