Nurse-led respiratory care bundle and pneumonia prevention in critically ill patients with abdominal sepsis: a multicenter before-and-after controlled study
Main finding · Pneumonia incidenceResult — go to the resultOdds ratio 0.39 95% CI 0.28–0.54Authors' conclusion
The nurse-led respiratory care bundle was associated with a lower incidence of pneumonia, shorter hospital stays, and lower 28-day mortality in patients with abdominal sepsis.
Study context
- Population
- Patients with abdominal sepsis
- Participants
- 869 patients
- Comparison
- Nurse-led respiratory care bundle vs traditional respiratory care
- Interventionn = 606
- Controln = 263reference
- Outcome
- Pneumonia incidence
Methodological detailsmultivariable logistic regression, sensitivity analyses (propensity score matching, inverse probability of treatment weighting, generalized estimating equations, mixed-effects models, Bootstrap resampling)
- Multivariable logistic regression
- Sensitivity analyses (propensity score matching, inverse probability of treatment weighting, generalized estimating equations, mixed-effects models, Bootstrap resampling)
Main finding
As reported in the abstract
Odds ratio
0.39
95% CI 0.28–0.54
P < 0.001
By group
Intervention vs Control
OR 0.39 (95% CI 0.28–0.54); P < 0.001
Further findings
| Outcome | Intervention | Control | Estimate | P value | |
|---|---|---|---|---|---|
| Hospital stayShorter in intervention group | IRR 0.80 (95% CI 0.71–0.90) | P < 0.001 | |||
| 28-day mortality | 18.3% | 22.8% | OR 0.66 (95% CI 0.45–0.95) | P = 0.025 | |
| 0.512Ratio (log scale) |
Original publication
Nurse-led respiratory care bundle and pneumonia prevention in critically ill patients with abdominal sepsis: a multicenter before-and-after controlled study. Crit Care. Published 14 September 2026. doi:10.
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