Opioid Consumption After Laparoscopic Radical Nephrectomy in Early Postoperative Recovery Phase: A Retrospective Cohort Study
Authors' conclusion
Based on the results of this study, epidural analgesia was associated with increased opioid consumption after laparoscopic radical nephrectomy.
Study context
- Population
- Patients undergoing elective laparoscopic radical nephrectomy
- Participants
- 226 patients
- Exposure
- Epidural analgesia vs no epidural analgesia
- Epiduraln = 188
- Outcome
- Epidural, IV and oral opioid consumption and factors associated with increased opioid amounts
- Follow-up
- First 3 postoperative days
Methodological detailsmultivariate analysis
- Multivariate analysis
Main finding
As reported in the abstract
Opioid consumption
- Epidural analgesia associated with increased opioid consumption in all 3 postoperative days
- Female gender a significant risk factor for increased opioid consumption (multivariate analysis)
- Higher BMI negatively correlated with high opioid consumption
Observational data: associations, not effects.
Original publication
Opioid Consumption After Laparoscopic Radical Nephrectomy in Early Postoperative Recovery Phase: A Retrospective Cohort Study. Acta Anaesthesiol Scand. Published 7 December 2025. doi:10.
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