Pain medicine

Postoperative analgesic effects of combined transversus abdominis plane block and anterior approach of sacral plexus block in patients undergoing laparoscopic radical prostatectomy: A randomized controlled trial

J Clin AnesthPublished Randomised controlled trial

Authors' conclusion

The addition of the anterior approach of SPB was not superior to TAPB alone in reducing opioid consumption for laparoscopic radical prostatectomy. However, it was associated with lower early postoperative pain scores, decreased incidence of catheter-related bladder discomfort, and improved quality of recovery.

Study context

Population
Patients aged 40 to 80 years, American Society of Anesthesiologists (ASA) I–III, undergoing elective laparoscopic radical prostatectomy under GA
Participants
90 patients
Comparison
TAP block plus anterior approach sacral plexus block vs TAP block alone
Primary endpoint
Cumulative IV morphine equivalent consumption
Follow-up
24 h postoperatively
Methodological detailsdouble-blinded, prospective, University-affiliated tertiary care hospital
  • Double-blinded
  • Prospective
  • University-affiliated tertiary care hospital

Primary result

As reported in the abstract

Secondary outcomes

Catheter-related bladder discomfort incidence · 1 h, 4 h and 8 h after surgery

Significantly lower in the sacral plexus block (SPB) group

Pain scores, time to first patient-controlled analgesia (PCA) demand, QoR-15

SPB decreased pain scores at 1 h, prolonged time to first PCA demand and increased QoR-15 at 48 h

Satisfaction, rescue analgesia, time to first flatus and ambulation

No significant differences

Safety

Adverse effects

No significant differences in incidence

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Postoperative analgesic effects of combined transversus abdominis plane block and anterior approach of sacral plexus block in patients undergoing laparoscopic radical prostatectomy: A randomized controlled trial. J Clin Anesth. Published 9 May 2025. doi:10.1016/j.jclinane.2025.111864

Composed by AI from the published abstract and checked against it. How Briefs are made →

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