Pediatric anesthesia & critical care
Oral prednisolone for postoperative analgesia management in paediatrics tonsillectomy: A meta-analysis of published studies
Authors' conclusion
The current meta-analysis indicates that the administration of oral prednisolone postoperatively does not decrease postoperative pain in paediatric patients following tonsillectomy.
Study context
- Population
- Children undergoing tonsillectomy
- Comparison
- Oral prednisolone vs placebo after tonsillectomy
- Outcome
- Postoperative pain intensity
Methodological detailsGRADE assessment
- GRADE assessment
Pooled result
As reported in the abstract
Pain intensity
Prednisolone vs PlaceboMD (CI)
POD 1; I² = 84%, p of I² < 0.002
−0.38(−0.99 to 0.33)
POD 3; I² = 97%, p of I² < 0.0001
−1.02(−2.78 to 0.75)
POD 5–7; I² = 84%, p of I² < 0.001
−0.15(−0.35 to 0.04)
Further pooled results
- Oral prednisolone did not reduce PONV
Original publication
Oral prednisolone for postoperative analgesia management in paediatrics tonsillectomy: A meta-analysis of published studies. Anaesth Crit Care Pain Med. Published 21 November 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →