Obstetric anesthesia

Outcomes Associated with a Patient Blood Management Program in Major Obstetric Hemorrhage: A Retrospective Cohort Study

Anesth AnalgPublished Retrospective cohort study

Authors' conclusion

In women with a major obstetric hemorrhage of 2000 mL or greater, the implementation of an obstetric PBM program was associated with reduced blood product utilization, reduced costs, reduced anemia, and increased hemoglobin rise postdischarge.

Study context

Population
Women with major obstetric hemorrhage of 2000 mL or greater admitted to The Corniche Hospital, 2018–2023
Participants
353 women
Exposure
Baseline year vs final year of an obstetric patient blood management (PBM) program
Outcome
Units of red blood cell (RBC), fresh-frozen plasma (FFP) and platelets transfused
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

Mean units of RBCs, FFP and platelets transfused per admission

P for trend < 0.001

Observational data: associations, not effects.

Secondary outcomes

Hb rise 3 weeks postdischarge

OutcomeP value
Anaemia predelivery · 2018 vs 2023P for trend = 0.015
Pretransfusion Hb in nonactively bleeding patients · 2018 vs 2023P for trend < 0.001

Blood product-acquisition cost savings · 2018 vs 2023

Blood acquisition savings
US$ 175,705

Adjusted composite morbidity, hospital and high-dependency unit LOS

No changes in adjusted composite morbidity, hospital or high-dependency unit LOS

Safety

Adjusted composite morbidity (transfusion reaction, acute lung injury, thrombosis, sepsis, postpartum hysterectomy)

No changes in adjusted composite morbidity

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Outcomes Associated with a Patient Blood Management Program in Major Obstetric Hemorrhage: A Retrospective Cohort Study. Anesth Analg. Published 21 November 2024. doi:10.1213/ane.0000000000007292

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