Perioperative medicine & outcomes
Outcomes in patients with chronic heart failure undergoing non‐cardiac surgery: a secondary analysis of the METREPAIR international cohort study*
Primary result · Postoperative MACEResult — go to the resultOdds ratio 2.04 95% CI 1.59–2.60Authors' conclusion
Stable chronic heart failure is independently associated with major adverse cardiovascular events, mortality and severe postoperative complications when measured 30 days after non-cardiac surgery.
Study context
- Population
- Patients aged ≥ 45 y with increased cardiovascular risk undergoing non-cardiac surgery
- Participants
- 15,158 patients
- Comparison
- Stable chronic HF vs no chronic HF
- Chronic HFn = 3,880
- Primary endpoint
- Incidence of postoperative MACE
- Follow-up
- 30 days
Methodological detailsmultivariable logistic regression
- Multivariable logistic regression
Primary result
Postoperative MACE
Odds ratio
2.04
95% CI 1.59–2.60
Chronic HF vs No chronic HF
OR 2.04 (95% CI 1.59–2.60)
As reported in the abstract
Secondary outcomes
| Outcome | OR (95% CI) | |
|---|---|---|
| 30-day mortality | 1.50 (1.17–1.92) | |
| Severe in-hospital complications | 1.47 (1.30–1.66) | |
| 0.512Odds ratio (log scale) |
MACE with reduced ejection fraction (subgroup: HF with transthoracic echocardiogram)
| OR (95% CI) | ||
|---|---|---|
| Reduced ejection fraction | 2.0 (1.01–3.81) | |
| 0.20.5125Odds ratio (log scale) |
- MACE with reduced ejection fraction (subgroup: HF with transthoracic echocardiogram) — Transthoracic echocardiography performed in HF
- 1267 (32.7%)
- MACE with reduced ejection fraction (subgroup: HF with transthoracic echocardiogram) — Left ventricular ejection fraction < 40% in HF
- 146 (11.5%)
Original publication
Outcomes in patients with chronic heart failure undergoing non‐cardiac surgery: a secondary analysis of the METREPAIR international cohort study*. Anaesthesia. Published 15 April 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →