Outcomes of Abdominal Exploration in ECMO-Supported Patients: A Multicenter Intensive Care Unit (ICU) Cohort Study
Authors' conclusion
Disease severity scores (APACHE II, SOFA) and the diagnosis of mesenteric ischemia are significant factors influencing mortality in ECMO-supported patients undergoing abdominal exploration.
Study context
- Population
- ECMO-supported patients undergoing abdominal exploration for abdominal complications, 3 academic medical centersof 1,386 ECMO-supported patients
- Participants
- 56 patients
- Exposure
- Nonsurvivors vs survivors
- Nonsurvivorsn = 32
- Outcome
- In-hospital mortality and mortality risk factors
Methodological detailsmulticentre
- Multicentre
Main finding
As reported in the abstract
In-hospital mortality
Cohort in-hospital mortality (32 of 56)
57%
Observational data: associations, not effects.
Further findings
Age
Hospital LOS
ICU LOS
Pre-ECMO lactate · ECMO initiation · univariate analysis
P < 0.001
| Outcome | Nonsurvivors | Survivors | P value |
|---|---|---|---|
| APACHE II score at ICU admissionUnivariate analysis | 17 | 9 | P < 0.001 |
| SOFA score at ICU admissionUnivariate analysis | 8 | 4 | P < 0.01 |
Age
- Similar in the two groups
Hospital LOS
- Significantly shorter in nonsurvivors
ICU LOS
- Significantly shorter in nonsurvivors
Operative and radiologic findings
- Most ischemic injuries watershed hypoperfusion; true thromboembolic occlusion uncommon
- Pneumatosis and free air corresponded to transmural necrosis and perforation
Original publication
Outcomes of Abdominal Exploration in ECMO-Supported Patients: A Multicenter ICU Cohort Study. J Cardiothorac Vasc Anesth. Published 20 January 2026. doi:10.
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