Sepsis & infection

Outcomes of critically ill older adults with COVID-19: a multicentre retrospective cohort study

Can J AnaesthPublished Retrospective cohort study

Authors' conclusion

Older critically ill COVID-19 patients had long ICU and hospital stays, and approximately half died in hospital.

Study context

Population
Patients ≥ 65 yr admitted to one of five Toronto intensive care unit (ICUs) with a primary diagnosis of SARS-CoV-2 infection, 11 March 2020–30 June 2021
Participants
273 patients · 5 ICUs
Exposure
Nonsurvivors vs survivors
  • Nonsurvivorsn = 131
  • Survivorsn = 142reference
Outcome
In-hospital mortality
Methodological detailsmulticentre, consecutive patients
  • Multicentre
  • Consecutive patients

Main finding

As reported in the abstract

Hospital survival

Survived hospital stay

142

52.0%

Observational data: associations, not effects.

Further findings

Age

P = 0.03

Female sex

P = 0.01

Hospital and ICU LOS; invasive mechanical ventilation

Hospital LOS, median [IQR]
19 [11-35] days
ICU LOS, median [IQR]
9 [5-22] days
Required invasive mechanical ventilation
164 (60.1%)
No significant differences in ICU LOS or duration of invasive mechanical ventilation between survivors and nonsurvivors

Original publication

Outcomes of critically ill older adults with COVID-19: a multicentre retrospective cohort study. Can J Anaesth. Published 11 July 2023. doi:10.1007/s12630-023-02518-y

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