Cardiothoracic & vascular anesthesia

Outcomes of Nasotracheal Versus Orotracheal Intubation in Neonates After Cardiopulmonary Bypass Surgery: A Retrospective Cross‐Sectional Analysis

Paediatr AnaesthPublished Retrospective cross-sectional study

Authors' conclusion

NI was not associated with improved exclusive oral feeding at discharge for neonatal cardiac surgical patients and may be associated with an increased risk of pressure injury in this single center, retrospective, cross-sectional study.

Study context

Population
Neonates intubated in the operating room undergoing CPB surgery, 2018 to 2020
Participants
179 neonates
Exposure
Nasal vs oral intubation
  • Oral intubation (OI)n = 89reference
  • Nasal intubation (NI)n = 90
Outcome
Unplanned extubation and oral feeding at discharge
Methodological detailssingle center
  • Single center

Main finding

As reported in the abstract

Unplanned extubation; exclusively oral feeding at ICU transfer or hospital discharge
  • No difference between NI and OI

Observational data: associations, not effects.

Secondary outcomes

Hospital LOS, duration of intubation, complications during induction

No difference

Sedation administration

Similar between the groups

Safety

OutcomeOR (95% CI)P value
Skin breakdown related to the ETT0.12 (0.01–0.65)P = 0.045
Skin breakdown related to the endotracheal tube (ETT) — Share of breakdown occurring in the NI group
89%

Original publication

Outcomes of Nasotracheal Versus Orotracheal Intubation in Neonates After Cardiopulmonary Bypass Surgery: A Retrospective Cross‐Sectional Analysis. Paediatr Anaesth. Published 9 July 2025. doi:10.1111/pan.70010

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