Organ support & nutrition

Outcomes of Patients Requiring Venoarterial Extracorporeal Membrane Oxygenation (VA-ECMO) for Cardiogenic Shock and Evaluation of Programmatic Changes

J Cardiothorac Vasc AnesthPublished Retrospective cohort study

Authors' conclusion

This study identifies a current mortality rate for patients with cardiogenic shock requiring VA-ECMO at 23.9%. This rate is lower than previously reported and coincides with beneficial programmatic changes to an ECMO program.

Study context

Population
Adults with cardiogenic shock requiring VA-ECMO at a tertiary care medical center, January 2012 to January 202546 in 2020–2025 era
Participants
134 adults
Exposure
Outcomes of VA-ECMO for cardiogenic shock across two eras
Outcome
Mortality, January 2020 to January 2025 era
Methodological detailssingle tertiary care centre
  • Single tertiary care centre

Main finding

As reported in the abstract

Overall mortality rate, 2020–2025 (n = 46)

23.9%

Observational data: associations, not effects.

Further findings

Hospital LOS, survivors vs nonsurvivors

P = 0.001

Survival to discharge, January 2012 to January 2025

Survival to discharge (n = 73)
50%

Characteristics associated with mortality

Procedure type
P = 0.025
RBC
P = 0.037
FFP
P = 0.030
Platelets
P = 0.044
Cryoprecipitate
P = 0.001
Longer CPB time
P = 0.005

Survival, heart transplantation subset (n = 22)

Survived (20 patients)
90.1%

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Outcomes of Patients Requiring VA-ECMO for Cardiogenic Shock and Evaluation of Programmatic Changes. J Cardiothorac Vasc Anesth. Published 22 April 2025. doi:10.1053/j.jvca.2025.04.025

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