Prognostic Factors Among Patients Receiving Microaxial Flow Pump for Acute Myocardial Infarction-Related Cardiogenic Shock: A Systematic Review and Meta-Analysis
Authors' conclusion
We identified several prognostic factors associated with short-term mortality in AMI-CS patients receiving mAFP support.
Study context
- Population
- Adults with acute myocardial infarction-related cardiogenic shock (AMI-CS) receiving microaxial flow pump (mAFP), excluding concurrent venoarterial ECMO and out-of-hospital cardiac arrest-only studies
- Participants
- 20,617 adults · 18 studies
- Outcome
- Factors associated with short-term mortality (high-certainty evidence)
Methodological detailsrandom-effects model, Quality in Prognosis Studies tool, GRADE certainty of evidence
- Random-effects model
- Quality in Prognosis Studies tool
- GRADE certainty of evidence
Pooled result
As reported in the abstract
Estimate (95% CI)
Increased age
aOR 1.04 per year(1.03–1.05)
Age ≥ 65 yr
aOR 2.42(0.77–7.64)
Female sex
aOR 1.26(1.09–1.45)
Higher BMI
aOR 1.05 per point(1.04–1.07)
Higher heart rate
aOR 1.02 per beats/min(1.01–1.02)
Higher serum creatinine
aOR 1.35 per mg/dL(1.08–1.70)
Mechanical ventilation
aOR 2.53(1.82–3.53)
Any vasopressors
aOR 1.52(1.11–2.08)
Vasopressors
aOR 1.37 per each vasopressor(1.18–1.58)
ST-elevation MI presentation
aOR 1.59(1.11–2.26)
Cardiac arrest
aOR 2.85(2.22–3.64)
Hypoxic-ischemic brain injury
aOR 5.36(3.03–9.47)
Each row per its own increment, as printed
Further pooled results
- Median short-term mortality across studies
- 50.7% (IQR 38.4-55.3%)
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Prognostic Factors Among Patients Receiving Microaxial Flow Pump for Acute Myocardial Infarction-Related Cardiogenic Shock: A Systematic Review and Meta-Analysis. Crit Care Med. Published 8 January 2026. doi:10.
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