Organ support & nutrition

Prognostic implication of venoarterial extracorporeal membrane oxygenation in acute myocardial infarction-related cardiogenic shock

J Intensive CarePublished Retrospective cohort study

Main finding · In-hospital mortalityResult — go to the resultOdds ratio 0.46 95% CI 0.29–0.75

Authors' conclusion

In this single-center study, AMI-CS was associated with a lower in-hospital mortality than non-AMI-CS after VA-ECMO treatment.

Study context

Population
Patients with cardiogenic shock (CS) treated with peripheral venoarterial extracorporeal membrane oxygenation (VA-ECMO) at a tertiary cardiovascular center, 2008–2023
Participants
667 patients
Exposure
AMI-CS vs non-AMI-CS in patients treated with peripheral VA-ECMO
Outcome
In-hospital mortality
Methodological detailssingle-centre, tertiary cardiovascular center, logistic regression, propensity score matching analysis
  • Single-centre
  • Tertiary cardiovascular center
  • Logistic regression
  • Propensity score matching analysis

Main finding

As reported in the abstract

Odds ratio

0.46

95% CI 0.29–0.75

P = 0.002

By group

AMI-CS vs non-AMI-CS
OR 0.46 (95% CI 0.29–0.75); P = 0.002

Observational data: associations, not effects.

Further findings

Cardiac arrest before VA-ECMO initiation

P < 0.001

Independent predictors of favorable outcomes after VA-ECMO

Younger age, shorter cardiac arrest duration, absence of severe left ventricular (LV) dysfunction, absence of RRT, higher hemoglobin, higher arterial pH, lower lactate

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Prognostic implication of venoarterial extracorporeal membrane oxygenation in acute myocardial infarction-related cardiogenic shock. J Intensive Care. Published 2 July 2025. doi:10.1186/s40560-025-00807-w

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