Outcomes of patients with respiratory failure declined for extracorporeal membrane oxygenation: a prospective observational study
Authors' conclusion
Nearly half of the patients declined for ECMO consideration were alive on day 7.
Study context
- Population
- Extracorporeal membrane oxygenation (ECMO) referrals for severe respiratory failure (COVID-19 and non-COVID-19) to Toronto General Hospital, 1 December 2019–30 November 2020147 with outcome data
- Participants
- 193 participants
- Exposure
- Declined vs accepted ECMO referrals
- Declinedn = 95
- Acceptedn = 52reference
- Outcome
- Referral outcome (accepted/declined) and patient outcome (alive/deceased)
- Follow-up
- Day 7
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Survival to day 7
| Group | Value | Too sick now | Too sick before | Not sick enough | Reason not reported |
|---|---|---|---|---|---|
| Declined | 49% | 35% | 53% | 100% | 50% |
| Accepted | 98% |
Value
Declined49%
Accepted98%
Too sick now
Declined35%
Accepted— not stated in the abstract
Too sick before
Declined53%
Accepted— not stated in the abstract
Not sick enough
Declined100%
Accepted— not stated in the abstract
Reason not reported
Declined50%
Accepted— not stated in the abstract
- Referrals declined for transfer
- 73%
Observational data: associations, not effects.
Further findings
Predictors of referral outcome
| OR (95% CI) | P value | ||
|---|---|---|---|
| Age | 0.97 (0.95–0.96) | P < 0.01 | |
| Involvement of other ECMO team members in discussion | 4.42 (1.28–15.2) | P < 0.01 | |
| 0.050.21520Odds ratio (log scale) |
Missing patient outcomes
- Referrals with missing patient outcome
- 46 (24%)
Original publication
Outcomes of patients with respiratory failure declined for extracorporeal membrane oxygenation: a prospective observational study. Can J Anaesth. Published 6 June 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →