Cardiothoracic & vascular anesthesia
Pan-Immune-Inflammation Value: A Novel Biomarker for Predicting Postoperative Atrial Fibrillation in Young Patients Undergoing Off-Pump Coronary Artery Bypass Grafting (CABG)
Main finding · PIV as predictor of postoperative new-onset AFResult — go to the resultOdds ratio 1.001 95% CI 1.000–1.002Authors' conclusion
Our study demonstrated for the first time in the literature that the PIV and the NLR significantly and independently predicted new-onset AF following off-pump CABG.
Study context
- Population
- Young patients (age ≤50 years) undergoing off-pump CABG, tertiary referral hospital in Turkey
- Participants
- 223 patients
- Exposure
- Atrial fibrillation (AF) vs non-AF after off-pump CABG
- AFn = 31
- non-AFn = 192reference
- Outcome
- PIV measurement
Methodological detailssingle-centre
- Single-centre
Main finding
PIV as predictor of postoperative new-onset AF
Odds ratio
1.001
95% CI 1.000–1.002
AF vs non-AF after off-pump CABG
OR 1.001 (95% CI 1.000–1.002)
As reported in the abstract
- PIV cut-off for predicting postoperative AF
- 307.9
- Sensitivity
- 93.5%
- Specificity
- 71.4%
Observational data: associations, not effects.
Further findings
Blood counts and inflammatory indices
- Platelet, neutrophil, lymphocyte, monocyte counts, neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio, systemic immune-inflammation index, systemic inflammation response index and PIV significantly different between groups
Preoperative clinical features, operative and postoperative data
- No significant differences between groups except hospital LOS
Original publication
Pan-Immune-Inflammation Value: A Novel Biomarker for Predicting Postoperative Atrial Fibrillation in Young Patients Undergoing Off-Pump CABG. J Cardiothorac Vasc Anesth. Published 5 March 2025. doi:10.
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