Pancreatic Stone Protein as Sepsis Biomarker in Patients Requiring Mechanical Circulatory Support: A Pilot Observational Study
Authors' conclusion
Patients supported with mechanical circulatory support who develop sepsis present with significantly higher PSP values than those who do not develop sepsis. PSP values are generally high in this population, even in patients not developing sepsis.
Study context
- Population
- Adults with cardiogenic shock requiring mechanical circulatory support, cardiac ICU
- Participants
- 32 adults
- Exposure
- Sepsis vs no sepsis
- Outcome
- Peak PSP
Methodological detailssingle-centre cardiac ICU
- Single-centre cardiac ICU
Main finding
As reported in the abstract
Observational data: associations, not effects.
Further findings
Sepsis incidence during ICU stay
- Patients developing sepsis
- 40%
Overall peak pancreatic stone protein (PSP) · peak on day 2
- Overall median peak PSP, ng/mL (IQR 222-601)
- 389.5
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Pancreatic Stone Protein as Sepsis Biomarker in Patients Requiring Mechanical Circulatory Support: A Pilot Observational Study. J Cardiothorac Vasc Anesth. Published 30 January 2025. doi:10.
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