Cardiothoracic & vascular anesthesia
Paravertebral analgesia versus wound infiltration in children recovering from cardiac surgery: a randomized controlled trial
Authors' conclusion
Paravertebral blocks reduced opioid consumption and pain during the first postoperative day in pediatric cardiac thoracotomies but did not accelerate recovery.
Study context
- Population
- Children aged 6–14 years with atrial or ventricular septal defects scheduled for cardiac surgery with CPB via thoracotomymean 7 years, 43% male
- Participants
- 100 children
- Comparison
- Paravertebral blocks vs Wound infiltration
- Paravertebral blocksn = 50
- Wound infiltrationn = 50reference
- Primary endpoint
- Total sufentanil (opioid) consumption
- Follow-up
- First 24 hours postsurgery
Methodological detailssingle-center, double-blind
- Single-center
- Double-blind
Primary result
As reported in the abstract
Total sufentanil consumption
P = 0.002
Further findings
| Outcome | Paravertebral blocks | Wound infiltration | P value |
|---|---|---|---|
| Faces Pain Scale-Revised pain scores · 6 hours postoperatively | 1.7 ± 2.2 | 3.3 ± 2.2 | P < 0.001 |
Faces Pain Scale-Revised pain scores · 6 hours postoperatively
- Pain scores consistently lower with paravertebral blocks at all time points (6, 12, 18, 24 h); largest difference at 6 h
Postoperative mechanical ventilation time, ICU stay, hospitalization
- Comparable
Safety
PONV
- Comparable
Original publication
Paravertebral analgesia versus wound infiltration in children recovering from cardiac surgery: a randomized controlled trial. Reg Anesth Pain Med. Published 14 May 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →