Neuroanesthesia & neurocritical care
Patients and relatives’ point of view on the choice of outcomes for a randomized-controlled trial in moderate-to-severe Traumatic Brain Injury
Study context
- Population
- Patients with brain injury and relatives (French National Association of Patients with Brain Injury, France Cérébrolésion), on outcomes for the COSMOS RCT of hypertonic saline in moderate-to-severe Traumatic Brain Injury (TBI)
- Participants
- 32 responders
- Exposure
- Relatives vs Former
- Relativesn = 19
- Formern = 13
- Outcome
- Outcomes rated relevant:
- Rather or entirely agreed
- 5-grade Likert scale
Methodological detailsonline survey, November to December 2024
- Online survey
- November to December 2024
Main finding
As reported in the abstract
- Mortality rated relevant
- 23 (71.9%)
- Activities of daily living rated relevant
- 26 (81.3%)
- Cognitive function rated relevant
- 27 (84.4%)
- Memory function rated relevant
- 30 (93.7%)
- Functional outcome rated relevant
- 17 (53.2%)
- Anxiety and depression symptoms rated relevant
- 26 (81.3%)
- Quality of life rated relevant
- 27 (84.4%)
Observational data: associations, not effects.
Further findings
Understanding of functional outcome
- Could not understand the concept of functional outcome
- 10 (31.3%)
Highest-ranked outcomes (highest mark of 7)
- Mortality
- 16
- Activities in daily living
- 14
- Memory
- 11
Original publication
Patients and relatives’ point of view on the choice of outcomes for a randomized-controlled trial in moderate-to-severe Traumatic Brain Injury. Anaesth Crit Care Pain Med. Published 6 May 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →