Respiratory failure & ventilation
Positive end-expiratory pressure (PEEP) titration and variability in renal venous congestion metrics in mechanically ventilated patients
Primary result · VII, IRVF patterns and RRI (PEEP 10 vs 5 cmH₂O)Result — go to the resultDifference 0.08 95% CI 0.01–0.14Authors' conclusion
In this exploratory study, increasing PEEP from 5 to 10 cmH₂O was associated with a higher VII, while IRVF patterns and RRI showed minimal change.
Study context
- Population
- Mechanically ventilated adults in the ICU of a tertiary hospital immediately prior to ventilator liberationanalysed
- Participants
- 35 participants
- Comparison
- PEEP 10 vs 5 cmH₂O
Methodological detailssingle-centre, exploratory
- Single-centre
- Exploratory
Primary result
VII, IRVF patterns and RRI (PEEP 10 vs 5 cmH₂O)
Difference
0.08
95% CI 0.01–0.14
PEEP 10 vs PEEP 5
difference 0.08 (95% CI 0.01–0.14)
As reported in the abstract
- Intrarenal venous flow (IRVF) patterns stable across PEEP levels; patients transitioning to a different IRVF pattern
- 3 (8.6%)
- Renal resistive index (RRI) did not change significantly with higher PEEP
- 0.005 (difference; 95% CI, −0.012 to 0.022)
Original publication
PEEP titration and variability in renal venous congestion metrics in mechanically ventilated patients. J Crit Care. Published 8 April 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →