Perioperative medicine & outcomes
Safety, Efficacy, and Cost-effectiveness of Outpatient Surgery for Uncomplicated Acute Appendicitis: The PENDI-CSI Randomized Clinical Trial
Authors' conclusion
Outpatient appendectomy is safe and effective for uncomplicated acute appendicitis.
Study context
- Population
- Patients aged older than 14 years with uncomplicated acute appendicitis (excluding pregnancy, neoplasms, inflammatory bowel disease, ASA IV)PENDI-CSI trial
- Participants
- 300 patients
- Comparison
- Outpatient vs inpatient appendectomy
- Outpatient surgery (OPS)n = 149
- Inpatient surgery (IPS)n = 151reference
Methodological detailsEnrolled October 2018 to June 2021
- Enrolled October 2018 to June 2021
Primary result
As reported in the abstract
Discharge without admission (OPS)
OPS
85.9%
128 of 149
Further findings
Predictors of admission in the OPS group
- Age over 31 years, RR
- 2.42 (1.04-5.65)
- Hypertension, RR
- 6.21 (3.22-11.97)
- Anesthetic risk II-III, RR
- 2.63 (1.17-5.94)
- Previous abdominal surgery, RR
- 3.34 (1.55-7.20)
- Postoperative pain VAS >6, RR
- 4.28 (2.67-6.86)
- Postoperative fear, RR
- 2.2 (1.04-4.67)
Perceived quality
- Similar in both groups
Hospital costs
- Savings per patient with the outpatient modality
- €1 034.97
- P < 0.001
Safety
Complications, readmissions, reinterventions · 1 month postoperatively
- No differences between groups
Original publication
Safety, Efficacy, and Cost-effectiveness of Outpatient Surgery for Uncomplicated Acute Appendicitis: The PENDI-CSI Randomized Clinical Trial. Ann Surg. Published 29 August 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →