Anaesthetic drugs & techniques

Performance of a new auxiliary device based on wrist brace to improve accuracy and feasibility in neuromuscular monitoring with acceleromyography in prone-positioned patients undergoing lumbar spine surgery: a prospective randomized clinical trial

J Clin Monit ComputPublished Randomised controlled trial

Study context

Population
Prone-positioned patients undergoing lumbar surgery under GA, rocuronium-induced NMB
Participants
57 patients
Comparison
AMG with wrist brace vs without brace
  • Bn = 29
  • NBn = 28reference
Primary endpoint
Precision of AMG (repeatability coefficients of T1 and TOF ratio from nine consecutive measurements) and agreement with EMG (Bland-Altman) in prone position
Methodological detailsprospective
  • Prospective

Primary result

As reported in the abstract

Repeatability coefficient of T1 · recovery to T1 of 25% and TOF ratio of 0.9
Repeatability coefficient of T1 significantly lower in B (higher precision), recovery to T1 25%
P = 0.017
Repeatability coefficient of T1 significantly lower in B (higher precision), recovery to train-of-four (TOF) ratio 0.9
0.033

Further findings

Mean difference of bias

OutcomeBNB
Agreement between AMG and EMG at TOF ratio of 0.9 (Bland-Altman)3.922 (95% limits of agreement - 21.83 to 29.67)6.839 (95% limits of agreement - 26.54 to 40.22)

Agreement between AMG and electromyography (EMG) at TOF ratio of 0.9 (Bland-Altman)

Wide limits of agreement in NB slightly narrowed in B but without significance

Original publication

Performance of a new auxiliary device based on wrist brace to improve accuracy and feasibility in neuromuscular monitoring with acceleromyography in prone-positioned patients undergoing lumbar spine surgery: a prospective randomized clinical trial. J Clin Monit Comput. Published 1 April 2023. doi:10.1007/s10877-023-01000-w

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