Pain medicine

Peri‐operative pain management in major lower extremity amputation in vascular Surgery: a UK anaesthetic and vascular surgery Delphi consensus study*

AnaesthesiaPublished Delphi consensus study

Authors' conclusion

This study provides the first procedure-specific consensus, delineating agreed principles and preferred pharmacological and locoregional analgesic approaches to peri-operative pain management in patients undergoing major lower extremity amputations.

Study context

Population
UK consultant anaesthetists and consultant vascular surgeons; peri-operative pain management in vascular surgical patients undergoing major lower extremity amputation
Participants
72 panellists
Outcome
Consensus on peri-operative pain management statements
Methodological detailsthree-round, online, modified Delphi, multispeciality expert panel
  • Three-round
  • Online
  • Modified Delphi
  • Multispeciality expert panel

Recommendations

As reported in the abstract

Consensus statements assessed

44

Statements reaching strong consensus agreement (incl. shared cross-speciality responsibility, mainstay role of locoregional analgesia, perineural catheters, opioid-sparing approaches, protocolised decision aids with individualisation of analgesia)

32

Statements with non-consensus (notably pre-amputation initiation of locoregional analgesia, ultrasound-guided nerve catheter placement, surgeon-delivered regional analgesia)

12

Further findings

Barriers to practices

Resource constraints and paucity of direct evidence

Original publication

Peri‐operative pain management in major lower extremity amputation in vascular Surgery: a UK anaesthetic and vascular surgery Delphi consensus study*. Anaesthesia. Published 17 December 2025. doi:10.1111/anae.70107

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