Perioperative medicine & outcomes
Peri‐operative risk of non‐cardiac surgery in patients with aortic stenosis: a systematic review and meta‐analysis
Pooled result · All-cause mortalityResult — go to the resultRelative risk 1.58 95% CI 1.18–2.12Authors' conclusion
Aortic stenosis in patients undergoing non-cardiac surgery is associated with a three-fold relative increase in the risk of mortality.
Study context
- Population
- Patients undergoing non-cardiac surgery
- Participants
- 100,486 patients · 19 studies
- Comparison
- Aortic stenosis vs no aortic stenosis in non-cardiac surgery
- Outcome
- All-cause in-hospital or 30-day mortality
- Follow-up
- In-hospital or 30 days
Pooled result
All-cause mortality
Relative risk
1.58
95% CI 1.18–2.12
P < 0.001
By group
Aortic stenosis
3.8%
95% CI 3.7–3.9%
Aortic stenosis vs No aortic stenosis
RR 1.58 (95% CI 1.18–2.12); P < 0.001
As reported in the abstract
Further pooled results
| Outcome | Values | RR (95% CI) | P value | |
|---|---|---|---|---|
| Postoperative MI | 1.79 (1.2–2.67) | P < 0.001 | ||
| Postoperative HF | 2.06 (1.19–3.59) | P < 0.001 | ||
| 0.20.5125Relative risk (log scale) |
| Outcome | Values |
|---|---|
| All-cause mortality, severe aortic stenosis (subgroup) | Severe aortic stenosis 9.6% (95% CI 7.7–12.1%) |
Original publication
Peri‐operative risk of non‐cardiac surgery in patients with aortic stenosis: a systematic review and meta‐analysis. Anaesthesia. Published 12 December 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →