Cardiothoracic & vascular anesthesia
Peri‐operative rehabilitation in patients undergoing elective cardiac valve surgery: a randomised controlled trial
Primary resultResult — go to the resultOdds ratio 0.88 95% CI 0.66–1.17Authors' conclusion
Peri-operative rehabilitation reduced the incidence of postoperative pulmonary complications in patients having surgery for valvular heart disease.
Study context
- Population
- Patients undergoing elective cardiac valve surgeryanalysed (ITT)
- Participants
- 818 patients
- Comparison
- Peri-operative rehabilitation bundle vs usual care
- Rehabilitationn = 399
- Usual caren = 419reference
- Primary endpoint
- Composite of:
- PPCs within first 7 days
- Prolonged postoperative hospitalisation > 7 days
- In-hospital all-cause mortality
Methodological detailssingle-centre
- Single-centre
Primary result
As reported in the abstract
Odds ratio
0.88
95% CI 0.66–1.17
P = 0.376
Events by treatment group
Rehabilitation vs Usual care
OR 0.88 (95% CI 0.66–1.17); P = 0.376
Secondary outcomes
| Outcome | Usual care | Rehabilitation | OR (95% CI) | P value | |
|---|---|---|---|---|---|
| PPCs | 47.1% | 40.4% | 0.720 (0.541–0.956) | P = 0.023 | |
| 0.512Odds ratio (log scale) |
Postoperative hospital stay > 7 days; in-hospital mortality
- No significant difference between the groups
Original publication
Peri‐operative rehabilitation in patients undergoing elective cardiac valve surgery: a randomised controlled trial. Anaesthesia. Published 21 October 2025. doi:10. 1111/ anae. 70025
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