Cardiothoracic & vascular anesthesia

Peri‐operative rehabilitation in patients undergoing elective cardiac valve surgery: a randomised controlled trial

AnaesthesiaPublished Randomised controlled trial

Primary resultResult — go to the resultOdds ratio 0.88 95% CI 0.66–1.17

Authors' conclusion

Peri-operative rehabilitation reduced the incidence of postoperative pulmonary complications in patients having surgery for valvular heart disease.

Study context

Population
Patients undergoing elective cardiac valve surgeryanalysed (ITT)
Participants
818 patients
Comparison
Peri-operative rehabilitation bundle vs usual care
  • Rehabilitationn = 399
  • Usual caren = 419reference
Primary endpoint
Composite of:
  • PPCs within first 7 days
  • Prolonged postoperative hospitalisation > 7 days
  • In-hospital all-cause mortality
Methodological detailssingle-centre
  • Single-centre

Primary result

As reported in the abstract

Odds ratio

0.88

95% CI 0.66–1.17

P = 0.376

Events by treatment group

Rehabilitation vs Usual care
OR 0.88 (95% CI 0.66–1.17); P = 0.376

Secondary outcomes

OutcomeUsual careRehabilitationOR (95% CI)P value
PPCs47.1%40.4%0.720 (0.541–0.956)P = 0.023

Postoperative hospital stay > 7 days; in-hospital mortality

No significant difference between the groups

Original publication

Peri‐operative rehabilitation in patients undergoing elective cardiac valve surgery: a randomised controlled trial. Anaesthesia. Published 21 October 2025. doi:10.1111/anae.70025

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