Obstetric anesthesia

Peri‐operative use of high‐flow nasal oxygen in obstetric patients: a systematic review

AnaesthesiaPublished Systematic review

Authors' conclusion

The advantages of peri-operative high-flow nasal oxygen over conventional oxygenation methods for obstetric patients remain uncertain.

Study context

Population
Obstetric patients in the peri-operative period11 articles
Comparison
HFNO vs facemask pre-oxygenation
Outcome
Maternal oxygenation and clinical outcomes
Methodological detailsrisk of bias assessment, 649 abstracts screened
  • Risk of bias assessment
  • 649 abstracts screened

Pooled result

As reported in the abstract

Pre-oxygenation
  • HFNO not superior to facemask pre-oxygenation in achieving target end-tidal oxygen concentrations
  • HFNO may increase PaO2; evidence of increased apnoea time inconsistent
  • Variation in pre-oxygenation strategies and primary outcomes

Safety

Maternal adverse effects and neonatal outcomes (Apgar scores, umbilical cord gases, fetal heart rate)

No reported adverse maternal effects or differences in neonatal outcomes

Original publication

Peri‐operative use of high‐flow nasal oxygen in obstetric patients: a systematic review. Anaesthesia. Published 18 June 2025. doi:10.1111/anae.16665

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